IRF-7 (phospho-Ser471/472) rabbit pAb

SKU: ES15429

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized phosho peptide around human IRF-7 (Ser471 and 472)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):55kD

Human_gene_id:3665

Human_swiss_prot_no:Q92985

Subcellular_location:Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus.

Other_name:Interferon regulatory factor 7 (IRF-7)

Background:IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008],