InVivoMAb Anti-Human IFNG/IFN-gamma (Iv0049)

SKU: HF813010

Size:100ug

Description:Iv0049 is a humanized monoclonal antibody that targets and neutralizes interferon-gamma (IFN-γ), a cytokine associated with inflammatory pathways. It has been investigated for potential use in autoimmune diseases such as Crohn’s disease. By binding IFN-γ, Iv0049 reduces downstream inflammatory signaling and its detrimental effects on intestinal barrier integrity. Early clinical studies have reported signs of therapeutic activity and generally manageable tolerability, although some serious adverse events, including disease exacerbation, were observed. Iv0049 has not been described as a currently marketed therapy, and its broader clinical development status remains unclear.

Host species:Human

Species reactivity:Human

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG1

Applications:ELISA, Neutralization, FCM

Target:Interferon gamma, IFN-gamma, Immune interferon, IFNG, IFN-γ

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Accession:P01579

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID:Iv0049

Product Usage Information:

Predicted molecular weight:

Note:For research use only. Not suitable for clinical or therapeutic use.