INTU Antibody, FITC conjugated - Cat. #: CSB-PA891544LC01HU

SKU: CSB-PA891544LC01HU

Size :50ug

Clone Number:

Aliases:Homolog of inturned (X. tropicalis) antibody; INT antibody; intu antibody; Inturned planar cell polarity effector homolog antibody; KIAA1284 antibody; PDZ domain containing 6 antibody; PDZ domain-containing protein 6 antibody; PDZD 6 antibody; PDZD6_HUMAN antibody; PDZK6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9ULD6

Immunogen:Recombinant Human Protein inturned protein (6-139AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:INTU

Research Areas:Cell biology; Stem cells