Insulin Receptor/INSR/CD220 Monoclonal Antibody

SKU: AN200037P

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Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:INSR

Target Synonym:HHF;CD220;HHF5;INSR;IR;Insulin R;INSR;IR;Insulin Receptor

Research Areas:Signal Transduction;Neuroscience;Cancer;Cardiovascular;Metabolism;Developmental Biology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:IHC-P

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:12G3

UNIProt ID:P06213

Accession:

Background:This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Concentration:1 mg/mL

Immunogen:Recombinant Human Insulin Receptor/INSR/CD220 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;

Calculated MW:

ObservedMW: