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GeneBio Systems

INHBA Polyclonal Antibody

INHBA Polyclonal Antibody

SKU:E-AB-15512

Regular price £424.00 GBP
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: INHBA

Target Synonym: Activin beta-A chain;EDF;Erythroid differentiation factor;Erythroid differentiation protein;Follicle stimulating hormone releasing protein;FRP;FSH releasing protein;INHBA;INHBA;Inhibin beta A chain;Inhibin beta A subunit;Inhibin;beta 1;Inhibin;beta A (activin A;activin AB alpha polypeptide)

Research Areas: Cancer;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P08476

Accession:

Background: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human INHBA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:1000-1:2000

Calculated MW: 47kDa

ObservedMW:

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