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Gene Bio Systems

IL1R2 Antibody - Cat. #: CSB-PA011622ESR1HU

IL1R2 Antibody - Cat. #: CSB-PA011622ESR1HU

CSB-PA011622ESR1HU

£291.00 GBP
£291.00 GBP
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Size :50ul

Clone Number:

Aliases:IL1 Receptor II antibody; Antigen CDw121b antibody; CD121 antibody; CD121 antigen-like family member B antibody; CD121b antibody; CD121B Antigen antibody; CDw121b antibody; IL 1 type II receptor antibody; IL-1R-2 antibody; IL-1R-beta antibody; IL-1R2 antibody; IL-1RT-2 antibody; IL-1RT2 antibody; IL1R Beta antibody; Il1r-2 antibody; IL1R2 antibody; IL1R2_HUMAN antibody; IL1R2c antibody; IL1RB antibody; Interleukin 1 receptor type II variant 3 antibody; Interleukin 1 receptor; beta; type II antibody; Interleukin 1 receptor; type II antibody; Interleukin-1 receptor beta antibody; Interleukin-1 receptor type 2 antibody; Interleukin-1 receptor type II antibody; MGC137383 antibody; MGC47725 antibody; OTTHUMP00000207969 antibody; p68 antibody; Type II interleukin-1 receptor; beta antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P27930

Immunogen:Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; Recommended dilution: WB:1:200-1:1000

Background:Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IL1R2

Research Areas:Cardiovascular; Immunology; Stem cells

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