IL17RC antibody , Cat. # FNab04231

SKU: FNab04231

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA(PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA(PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA(PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1(PubMed:16785495). Isoform 5: Receptor for both IL17A and IL17F. Isoform 6: Does not bind IL17A or IL17F. Isoform 7: Does not bind IL17A or IL17F. Isoform 8: Receptor for both IL17A and IL17F.

Immunogen:interleukin 17 receptor C

Synonyms:

Observed MW:45-50kd

Uniprot ID:Q8NAC3

Reactivity:Human, Mouse

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:84818

Research Area:Immunology, cancer