IL10RA Polyclonal Antibody

SKU: E-AB-13869

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: IL10RA

Target Synonym: CD210;CDw210a;CDw210a antigen;HIL 10R;HIL10R;I10R1;IL 10R 1;IL 10R A;IL 10R;IL 10R1;IL-10 receptor subunit alpha;IL-10R subunit 1;IL-10R subunit alpha;IL-10R1;IL-10RA;IL10R;IL10R1;IL10RA;Interleukin 10 receptor alpha;Interleukin 10 receptor alpha chain;Interleukin-10 receptor subunit 1;Interleukin-10 receptor subunit alpha

Research Areas: Cancer;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13651

Accession:

Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human IL10RA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: