IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody

SKU: BT-AP09005

Size:100μL

Background:This gene encodes a member of the serine/threonine protein kinase family. The encoded protein| a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex| phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway| thereby activating the transcription factor.

Research_area:Cancer; Cardiovascular; Cell biology; Signal transduction; Immunology

Target_protein:CHUK

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Inhibitor of nuclear factor kappa-B kinase subunit alpha

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):84654;86564

UniProt accession:Human: O15111/O14920; Rat: Q9QY78

Synonyms:Inhibitor of nuclear factor kappa-B kinase subunit alpha; CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B

GeneID:Human: 1147/3551; Mouse: 16150; Rat: 84351