IFNA1 Antibody - Cat. #: CSB-PA365592KA01HU

SKU: CSB-PA365592KA01HU

Size :100ul

Clone Number:

Aliases:IFL antibody; IFN alpha antibody; IFN alpha 1/13 antibody; IFN alpha 1b antibody; IFN alphaD antibody; IFN antibody; IFN-alpha-1/13 antibody; IFNA@ antibody; IFNA1 antibody; IFNA1_HUMAN antibody; IFNA13 antibody; Interferon alpha 1 antibody; Interferon alpha-1/13 antibody; Interferon alpha-D antibody; Interferon alpha1 antibody; Interferon, alpha 13 antibody; LeIF D antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P01562

Immunogen:Recombinant protein of Human IFN-?

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:2000

Background:Interferon-?1 is a member of the Type I IFN family best known for their antiviral activity. Most nucleated cells produce one or more Type I IFNs in response to viral infection. Secreted Type I IFN then induces viral protective responses in neighboring non-infected cells. Type I IFNs also enhance virus-induced apoptosis. Other IFN-?1 activities include enhancement of dendritic cell maturation and cytotoxic T cell activity. IFN-?1 binds to the IFN-?R1 and IFN-?R2 heterodimer. Intracellular signaling through the Jak/Stat pathway is best characterized. However, the PI3K, ERK, and p38 kinase pathways are also involved. The antiviral activities of the IFNs have led to their use in treating viral infections. Type I IFNs also appear to have an integral role in several autoimmune diseases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Affinity purification

Conjugate:Non-conjugated

Buffer:Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IFNA1

Research Areas:Cancer;Immunology