IDO2 Polyclonal Antibody

SKU: E-AB-18375

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: IDO2

Target Synonym: 3-dioxygenase 2;3-dioxygenase-like protein 1;EC 1.13.11.;I23O2;IDO 2;IDO-2;Ido2;INDOL 1;Indoleamine 2;Indoleamine 2;3 dioxygenase 2;Indoleamine 2;3 dioxygenase like 1 protein;Indoleamine 2;3 dioxygenase like protein 1;Indoleamine pyrrole 2;3 dioxygenase like 1;Indoleamine pyrrole 2;3 dioxygenase like protein 1;Indoleamine-pyrrole 2

Research Areas: Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q6ZQW0

Accession:

Background: INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

Concentration: 1 mg/mL

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:30-1:150

Calculated MW: 45 kDa

ObservedMW: Refer to figures