Human Vitamin D Receptor,VDR ELISA KIT

SKU: E1553Hu

Size:96 Tests-1 Kit

Background:Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:28698609, PubMed:16913708, PubMed:15728261, PubMed:10678179). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed:28698609). Plays a central role in calcium homeostasis (By similarity). {ECO:0000250|UniProtKB:P13053, ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:15728261, ECO:0000269|PubMed:16913708, ECO:0000269|PubMed:28698609}.

Research_area:

Applications:ELISA

Target_protein:VDR

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.33ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Vitamin D Receptor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11473

MASS(Da):48289

GeneID:7421

Synonyms:VDR NR1I1

Gene names:VDR

Standard solution:3200ng/L