Human Urate Transporter 1, URAT1 ELISA Kit

SKU: E3340Hu

Size:96 Tests-1 Kit

Background:Urea Channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane Channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.

Research_area:Metabolism

Applications:ELISA

Target_protein:SLC14A1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.043ng/ml

Detection range:0.1-38ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Urate Transporter 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13336

MASS(Da):42,528

GeneID:6563

Synonyms:SLC14A1;Solute carrier family 14 member 1;Urea transporter 1;Urea transporter, erythrocyte

Gene names:SLC14A1

Standard solution:40ng/ml