Human Ubiquitin Carboxyl Terminalhydrolase Bap1, BAP1 ELISA Kit

SKU: E3920Hu

Size:96 Tests-1 Kit

Background:BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) is a deubiquitinating enzyme that in humans is encoded by the BAP1 gene. BAP1 encodes an 80.4 kDa nuclear-localizing protein with a ubiquitin carboxy-terminal hydrolase (UCH) domain that gives BAP1 its deubiquitinase activity. Recent studies have shown that BAP1 and its fruit fly homolog, Calypso, are members of the polycomb-group proteins (PcG) of highly conserved transcriptional repressors required for long-term silencing of genes that regulate cell fate determination, stem cell pluripotency, and other developmental processes.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:BAP1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.91ng/ml

Detection range:20-7000ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ubiquitin carboxyl terminal hydrolase BAP1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92560

MASS(Da):80,362

GeneID:8314

Synonyms:BAP1;BRCA1-associated protein 1;Cerebral protein 6;HUCEP-13;hucep-6;Ubiquitin carboxyl-terminal hydrolase BAP1;UCHL2

Gene names:BAP1

Standard solution:8000ng/ml