Human Tumor necrosis factor receptor superfamily member 6,FAS ELISA KIT

SKU: E6986Hu

Size:96 Tests-1 Kit

Background:Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). {ECO:0000269|PubMed:19118384, ECO:0000269|PubMed:7533181}.

Research_area:

Applications:ELISA

Target_protein:FAS

Reactivity:Human

Assay type:Sandwich

Sensitivity:54.2ng/L

Detection range:100-6400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Tumor necrosis factor receptor superfamily member 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P25445

MASS(Da):37732

GeneID:355

Synonyms:FAS APT1 FAS1 TNFRSF6

Gene names:FAS

Standard solution:12800ng/L