Human Tumor Necrosis Factor Receptor Superfamily Member 1B, TNFRSF1B ELISA Kit

SKU: E6846Hu

Size:96 Tests-1 Kit

Background:Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:TNFRSF1B

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.98ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Tumor Necrosis Factor Receptor Superfamily Member 1B

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P20333

MASS(Da):48,291

GeneID:7133

Synonyms:CD antigen CD120b;Etanercept;p75;p80 TNF-alpha receptor;TBP-2;TBPII;TNF-R2;TNFR-II;TNF-RII;TNFRSF 1B;TNFRSF1B;Tumor necrosis factor receptor 2;Tumor necrosis factor receptor superfamily member 1B;Tumor necrosis factor receptor superfamily member 1b, membrane form;Tumor necrosis factor receptor type II;Tumor necrosis factor-binding protein 2

Gene names:TNFRSF1B

Standard solution:4000ng/L