Human Tumor necrosis factor-associated factor 1,TRAF1 ELISA KIT

SKU: E6346Hu

Size:96 Tests-1 Kit

Background:Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2. {ECO:0000269|PubMed:10692572, ECO:0000269|PubMed:16323247, ECO:0000269|PubMed:18429822, ECO:0000269|PubMed:19287455, ECO:0000269|PubMed:19698991, ECO:0000269|PubMed:20385093}.

Research_area:

Applications:ELISA

Target_protein:TRAF1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.29ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Tumor necrosis factor-associated factor 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13077

MASS(Da):46164

GeneID:7185

Synonyms:TRAF1 EBI6

Gene names:TRAF1

Standard solution:4800ng/L