Human Transmembrane Protease Serine 4, TMPRSS4 ELISA Kit

SKU: E6311Hu

Size:96 Tests-1 Kit

Background:Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity (PubMed:24434139). Seems to be capable of activating ENaC (By similarity). (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.

Research_area:Neuroscience; Cell Biology; Cancer

Applications:ELISA

Target_protein:TMPRSS4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.019ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Transmembrane protease serine 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NRS4

MASS(Da):48,246

GeneID:56649

Synonyms:CAP2;CAPH2;Channel-activating protease 2;Membrane-type serine protease 2;MT-SP2;TMPRSS3;TMPRSS4;Transmembrane protease serine 4;Transmembrane protease serine 4 catalytic chain];

Gene names:TMPRSS4

Standard solution:24ng/mL