Human Transcription Factor Sox-2, SOX2 ELISA Kit

SKU: E6291Hu

Size:96 Tests-1 Kit

Background:Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Binds to the proximal enhancer region of NANOG (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency (PubMed: 18035408). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). May function as a switch in neuronal development (By similarity).

Research_area:Neuroscience

Applications:ELISA

Target_protein:SOX2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.019ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription Factor Sox-2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P48431

MASS(Da):34,310

GeneID:6657

Synonyms:SOX 2;SOX2;Transcription factor SOX-2

Gene names:SOX2

Standard solution:24ng/mL