Human Toll Interacting Protein, TOLLIP ELISA Kit

SKU: E6281Hu

Size:96 Tests-1 Kit

Background:Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).

Research_area:Others

Applications:ELISA

Target_protein:TOLLIP

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.18ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Toll Interacting Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H0E2

MASS(Da):30,282

GeneID:54472

Synonyms:IL-1RAcPIP;Toll-interacting protein;TOLLIP

Gene names:TOLLIP

Standard solution:2400ng/L