Human TNFSF12/Tweak ELISA Kit PicoKine®

SKU: EK0920

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TNFSF12

Specificity: Natural and recombinant human TNFSF12

Background: Tumor necrosis factor ligand superfamily member 12 also known as TNF-related weak inducer of apoptosis (TWEAK) is a protein that in humans is encoded by the TNFSF12 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator ofangiogenesis. The TNFSF12 gene lies 878 bp upstream of the putative transcriptional start site of the TNFSF13 gene on chromosome 17p13.1.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: S94-H249

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Reference:

Uniprot ID: O43508

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 8742

Protein Name: Tumor necrosis factor ligand superfamily member 12

Gene Full Name: TNF superfamily member 12

Synonyms: TNF superfamily member 12; APO3L; DR3LG; TNLG4A; TWEAK; TNFSF12