Human Thyroglobulin, TG ELISA Kit

SKU: E0008Hu

Size:96 Tests-1 Kit

Background:Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed: 32025030, PubMed: 17532758). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (PubMed: 32025030). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (PubMed: 32025030). One dimer produces 7 thyroid hormone molecules (PubMed: 32025030).

Research_area:Metabolism

Applications:ELISA

Target_protein:TG

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.021ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Thyroglobulin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P01266

MASS(Da):304,790

GeneID:7038

Synonyms:Tg;Thyroglobulin

Gene names:TG

Standard solution:32ng/ml