Human Terf1 Interacting Nuclear Factor 2, TINF2 ELISA Kit

SKU: E6467Hu

Size:96 Tests-1 Kit

Background:Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Research_area:Others

Applications:ELISA

Target_protein:TINF2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.027ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Terf1 Interacting Nuclear Factor 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BSI4

MASS(Da):50,023

GeneID:26277

Synonyms:TERF1-interacting nuclear factor 2;TINF 2;TINF2;TRF1-interacting nuclear protein 2

Gene names:TINF2

Standard solution:32ng/ml