Human STEAP family member 4,Steap4 ELISA KIT

SKU: E0633Hu

Size:96 Tests-1 Kit

Background:Integral membrane protein that functions as NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (PubMed:30337524). Can also reduce Cu(2+) to Cu(1+) (By similarity). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance (PubMed:18430367, PubMed:18381574). Involved in inflammatory arthritis, through the regulation of inflammatory cytokines (PubMed:19660107). Inhibits anchorage-independent cell proliferation (PubMed:19787193). {ECO:0000250|UniProtKB:Q923B6, ECO:0000269|PubMed:18381574, ECO:0000269|PubMed:18430367, ECO:0000269|PubMed:19660107, ECO:0000269|PubMed:19787193, ECO:0000269|PubMed:30337524}.

Research_area:

Applications:ELISA

Target_protein:STEAP4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.02ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:STEAP family member 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q687X5

MASS(Da):51981

GeneID:79689

Synonyms:STEAP4 STAMP2 TNFAIP9

Gene names:STEAP4

Standard solution:16ng/ml