Human Siglec5/Cd170 ELISA Kit PicoKine®

SKU: EK1583

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: SIGLEC5

Specificity: Natural and recombinant human Siglec5

Background: Sialic acid-binding Ig-like lectin 5 is a protein that in humans is encoded by the SIGLEC5 gene. This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E17-L441

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Reference:

Uniprot ID: O15389

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 8778

Protein Name: Sialic acid-binding Ig-like lectin 5

Gene Full Name: sialic acid binding Ig like lectin 5

Synonyms: CD170; CD33 antigen like 2; CD33L2; OB binding protein 2; OB BP2; OBBP2; Obesity binding protein 2; SIGLEC 5; SIGLEC5