Human SCF/KITLG/Kit ligand ELISA Kit PicoKine®

SKU: EK0507

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: KITLG

Specificity: Natural and recombinant human SCF

Background: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). It is mapped to 12q21.32. SCF was primarily expressed by perivascular cells throughout the bone marrow, and it plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF can exist both as a transmembrane protein and a soluble protein. This gene plays an important role in the hematopoiesis during embryonic development. During development, the presence of the SCF also plays an important role in the localization of melanocytes, cells that produce melanin and control pigmentation. In addition to it, SCF can promote mast cell adhesion, migration, proliferation, and survival. It also promotes the release of histamine and tryptase, which are involved in the allergic response.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: E26-A190

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Reference:

Uniprot ID: P21583

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Cross Reactivity: No cross reactivity with other proteins.

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Gene ID: 4254

Protein Name: Kit ligand

Gene Full Name: KIT ligand

Synonyms: c Kit ligand; KIT ligand; Kitl; KITLG; KL 1; Mast cell growth factor; MGF; SCF; SF; SHEP7; Stem cell factor