Human Sam Domain and Hd Domain-containing Protein 1, SAMHD1 ELISA Kit

SKU: E6116Hu

Size:96 Tests-1 Kit

Background:Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation (PubMed: 23776175). Regulates TRAF6 and MAP3K7 ubiquitination (PubMed: 23776175). Involved in the regulation of cell mobility (PubMed: 23333244, PubMed: 23776175, PubMed: 25315659). Regulates lipolysaccharide (LPS)-induced endothelial cell migration (PubMed: 23776175). Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis (PubMed: 23333244).

Research_area:Others

Applications:ELISA

Target_protein:SASH1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.32ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Sam Domain and Hd Domain-Containing Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O94885

MASS(Da):136,653

GeneID:23328

Synonyms:Proline-glutamate repeat-containing protein;SAM and SH3 domain-containing protein 1;SASH 1;SASH1

Gene names:SASH1

Standard solution:3200ng/L