Human Retinoblastoma-like,RBL1 ELISA KIT

SKU: E4322hu

Size:96 Tests-1 Kit

Background:Key regulator of entry into cell division (PubMed:17671431). Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation (By similarity). Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression (By similarity). Controls histone H4 'Lys-20' trimethylation (By similarity). Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters (By similarity). Potent inhibitor of E2F-mediated trans-activation (PubMed:8319904). May act as a tumor suppressor (PubMed:8319904). {ECO:0000250|UniProtKB:Q64701, ECO:0000269|PubMed:17671431, ECO:0000269|PubMed:8319904}.

Research_area:

Applications:ELISA

Target_protein:RBL1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.023ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Retinoblastoma-like

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P28749

MASS(Da):120847

GeneID:5933

Synonyms:RBL1

Gene names:RBL1

Standard solution:24ng/ml