Human Reticulon-4 Receptor-like 2, RTN4RL2 ELISA Kit

SKU: E6082Hu

Size:96 Tests-1 Kit

Background:Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).

Research_area:Neuroscience

Applications:ELISA

Target_protein:RTN4RL2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.021ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Reticulon-4 Receptor-Like 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q86UN3

MASS(Da):46,106

GeneID:349667

Synonyms:NgR2;Nogo receptor-like 3;Nogo-66 receptor homolog 1;Nogo-66 receptor-related protein 2;Reticulon-4 receptor-like 2;RTN 4RL2;RTN4RL2

Gene names:RTN4RL2

Standard solution:24ng/mL