Human RET ELISA Kit PicoKine®

SKU: EK1877

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: RET

Specificity: Natural and recombinant human RET

Background: This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. It is mapped to 10q11.21. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L29-R635

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P07949

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 5979

Protein Name: Proto-oncogene tyrosine-protein kinase receptor Ret

Gene Full Name: ret proto-oncogene

Synonyms: ret proto-oncogene; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC-ELE1; RET