Human Renalase, RNLS ELISA Kit

SKU: E3109Hu

Size:96 Tests-1 Kit

Background:Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

Research_area:Cell Biology

Applications:ELISA

Target_protein:RNLS

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.52ng/ml

Detection range:1-400ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Renalase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5VYX0

MASS(Da):37,847

GeneID:55328

Synonyms:MAO-C;Monoamine oxidase-C;Renalase;RNLS

Gene names:RNLS

Standard solution:480ng/ml