Human PTH1R ELISA Kit PicoKine®

SKU: EK2087

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PTH1R

Specificity: Natural and recombinant human PTH1R

Background: Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as parathyroid hormone 1 receptor (PTH1R), is a protein that in humans is encoded by the PTH1R gene. It is mapped to 3p21.31. The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Immunogen: Expression system for standard: CHO; Immunogen sequence: Y23-M189

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Reference:

Uniprot ID: Q03431

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 5745

Protein Name: Parathyroid hormone/parathyroid hormone-related peptide receptor

Gene Full Name: parathyroid hormone 1 receptor

Synonyms: parathyroid hormone 1 receptor; PFE; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTH1R; PTHR; PTHR1