Human Protein Phosphatase 2A, PP2A ELISA Kit

SKU: E6870Hu

Size:96 Tests-1 Kit

Background:Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.

Research_area:Others

Applications:ELISA

Target_protein:PPM1A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.018ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Protein Phosphatase 2A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35813

MASS(Da):42,448

GeneID:5494

Synonyms:PP2C-alpha;PPM 1A;PPM1A;Protein phosphatase 1A;Protein phosphatase 2C isoform alpha;Protein phosphatase IA

Gene names:PPM1A

Standard solution:12.8ng/ml