Human Protein Arginine N-methyltransferase 2, PRMT2 ELISA Kit

SKU: E5953Hu

Size:96 Tests-1 Kit

Background:Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:PRMT2

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.13ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein arginine N-methyltransferase 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P55345

MASS(Da):49,042

GeneID:3275

Synonyms:Histone-arginine N-methyltransferase PRMT2;HRMT1L1;PRMT2;Protein arginine N-methyltransferase 2

Gene names:PRMT2

Standard solution:4800ng/L