Human proteasome(prosome, macropain) subunit, beta type, 1,PSMB1 ELISA KIT

SKU: E5946Hu

Size:96 Tests-1 Kit

Background:Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). {ECO:0000269|PubMed:15244466, ECO:0000269|PubMed:27176742, ECO:0000269|PubMed:8610016}.

Research_area:

Applications:ELISA

Target_protein:PSMB1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.81ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:proteasome(prosome, macropain) subunit, beta type, 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P20618

MASS(Da):26489

GeneID:5689

Synonyms:PSMB1 PSC5

Gene names:PSMB1

Standard solution:3200ng/L