Human Phosphodiesterase 9A,PDE9A ELISA KIT

SKU: E3573Hu

Size:96 Tests-1 Kit

Background:Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity). {ECO:0000250|UniProtKB:Q8QZV1, ECO:0000269|PubMed:18757755, ECO:0000269|PubMed:21483814, ECO:0000269|PubMed:25799991, ECO:0000269|PubMed:9624146, ECO:0000305}.

Research_area:

Applications:ELISA

Target_protein:PDE9A

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.23ng/ml

Detection range:2.5-160ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Phosphodiesterase 9A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O76083

MASS(Da):68493

GeneID:5152

Synonyms:PDE9A

Gene names:PDE9A

Standard solution:320ng/ml