Human Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3 or Vps34,PIK3C3 ELISA KIT

SKU: E7367Hu

Size:96 Tests-1 Kit

Background:Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. As part of PI3KC3-C1, promotes endoplasmic reticulum membrane curvature formation prior to vesicle budding (PubMed:32690950). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity). {ECO:0000250|UniProtKB:O88763, ECO:0000269|PubMed:14617358, ECO:0000269|PubMed:20208530, ECO:0000269|PubMed:20643123, ECO:0000269|PubMed:32690950, ECO:0000269|PubMed:7628435, ECO:0000305}.

Research_area:

Applications:ELISA

Target_protein:PIK3C3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.24ng/ml

Detection range:0.5-150ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3 or Vps34

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8NEB9

MASS(Da):101549

GeneID:5289

Synonyms:PIK3C3 VPS34

Gene names:PIK3C3

Standard solution:160ng/ml