Human Phosphatidylinositol 3,4, 5-Trisphosphate-dependent Rac Exchanger 2 Protein, PREX2 ELISA Kit

SKU: E7272Hu

Size:96 Tests-1 Kit

Background:Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:PREX2

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.88ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q70Z35

MASS(Da):182,622

GeneID:80243

Synonyms:DEP domain-containing protein 2;Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein;PREX 2;PREX2;P-Rex2;PtdIns(3,4,5-dependent Rac exchanger 2

Gene names:PREX2

Standard solution:2400ng/L