Human Phorbol-12-myristate-13-acetate-induced protein 1,PMAIP1 ELISA KIT

SKU: E7657Hu

Size:96 Tests-1 Kit

Background:Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. {ECO:0000250, ECO:0000269|PubMed:10807576, ECO:0000269|PubMed:15694340, ECO:0000269|PubMed:15705586, ECO:0000269|PubMed:17374615, ECO:0000269|PubMed:17389404}.

Research_area:

Applications:ELISA

Target_protein:PMAIP1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.06ng/ml

Detection range:0.13-8ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13794

MASS(Da):6030

GeneID:5366

Synonyms:PMAIP1 NOXA

Gene names:PMAIP1

Standard solution:16ng/ml