Human PGLYRP1 ELISA Kit PicoKine®

SKU: EK2267

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PGLYRP

Specificity: Natural and recombinant human PGLYRP

Background: Peptidoglycan recognition protein 1, PGLYRP1, also known as TAG7, is an antibacterial and pro-inflammatory innate immunity protein that in humans is encoded by the PGLYRP1 gene. Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-I and PGRP-I∫ are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q22-P196

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Reference:

Uniprot ID: O75594

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 8993

Protein Name: Peptidoglycan recognition protein 1

Gene Full Name: peptidoglycan recognition protein 1

Synonyms: Peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; SBBI68; UNQ639/PRO1269