Human NRCAM ELISA Kit PicoKine®

SKU: EK1408

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: NRCAM

Specificity: Natural and recombinant human NRCAM

Background: Neuronal cell adhesion molecule is a protein that in humans is encoded by the NRCAM gene. Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes ional signaling during axonal cone growth. Also, this gene is expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during ional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L30-N600

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Reference:

Uniprot ID: Q92823

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 4897

Protein Name: Neuronal cell adhesion molecule

Gene Full Name: neuronal cell adhesion molecule

Synonyms: hBravo; KIAA0343; neuronal cell adhesion molecule; Neuronal surface protein Bravo; Ng CAM related; Nr CAM; NRCAM