Human NGF/NGF beta ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ0469

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: NGF

Specificity: Natural and recombinant human NGF/NGF beta

Background: Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male mouse submaxillary gland (MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight (Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is human 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S122-A241

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Reference:

Uniprot ID: P01138

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4803

Protein Name: Beta-nerve growth factor

Gene Full Name: nerve growth factor

Synonyms: NGF; NGFB; Beta-nerve growth factor; Beta-NGF