Human Nedd8, NEDD8 ELISA Kit

SKU: E5744Hu

Size:96 Tests-1 Kit

Background:Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

Research_area:Cell Biology

Applications:ELISA

Target_protein:NEDD8

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.87ng/L

Detection range:20-3500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:NEDD8

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q15843

MASS(Da):9,072

GeneID:4738

Synonyms:NEDD8;NEDD-8;Neddylin;Neural precursor cell expressed developmentally down-regulated protein 8;Ubiquitin-like protein Nedd8

Gene names:NEDD8

Standard solution:4000ng/L