Human Mucolipin 2, MCOLN2 ELISA Kit

SKU: E2918Hu

Size:96 Tests-1 Kit

Background:Nonselective cation Channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation Channel with inwardly rectifying activity (PubMed: 19940139, PubMed: 19885840). May activate ARF6 and be involved in the trafficking of GPI-anchored cargo proteins to the cell surface via the ARF6-regulated recycling pathway (PubMed: 17662026). May play a role in immune processes. In adaptive immunity, TRPML2 and TRPML1 may play redundant roles in the function of the specialized lysosomes of B cells (By similarity). In the innate immune response, may play a role in the regulation of chemokine secretion and macrophage migration (By similarity). Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events (PubMed: 19885840).

Research_area:Others

Applications:ELISA

Target_protein:MCOLN2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.018ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Mucolipin 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8IZK6

MASS(Da):65,942

GeneID:255231

Synonyms:MCOLN 2;MCOLN2;Mucolipin-2;Transient receptor potential Channel mucolipin 2;TRPML2

Gene names:MCOLN2

Standard solution:12.8ng/ml