Human monocyte chemotactic protein 1;monocyte chemotactic and activating factor,MCP-1;MCAF ELISA KIT

SKU: E0124Hu

Size:96 Tests-1 Kit

Background:Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:9837883, PubMed:10587439, PubMed:10529171). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:9837883, PubMed:10587439). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8627182, PubMed:9792674, PubMed:8195247). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690). {ECO:0000269|PubMed:10529171, ECO:0000269|PubMed:10587439, ECO:0000269|PubMed:8107690, ECO:0000269|PubMed:8195247, ECO:0000269|PubMed:8627182, ECO:0000269|PubMed:9792674, ECO:0000269|PubMed:9837883}.

Research_area:

Applications:ELISA

Target_protein:CCL2

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.14ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:monocyte chemotactic protein 1;monocyte chemotactic and activating factor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P13500

MASS(Da):11025

GeneID:6347

Synonyms:CCL2 MCP1 SCYA2

Gene names:CCL2

Standard solution:4000ng/L