Human MMP-12 ELISA Kit PicoKine®

SKU: EK0950

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: MMP12

Specificity: Natural and recombinant human MMP-12

Background: Matrix metalloproteinase-12 (MMP12), also known as MME or ME, is an enzyme that in humans is encoded by the MMP12 gene. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.2. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. This gene may involved in tissue injury and remodeling.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L17-C470

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Reference:

Uniprot ID: P39900

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4321

Protein Name: Macrophage metalloelastase

Gene Full Name: matrix metallopeptidase 12

Synonyms: HME; Macrophage elastase; Macrophage metalloelastase; Matrix metalloproteinase 12; ME; MME; MMP 12; MMP12