Human Mitofusin-1,MFN1 ELISA KIT

SKU: E6963Hu

Size:96 Tests-1 Kit

Background:Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12475957, PubMed:12759376, PubMed:27920125, PubMed:28114303). Membrane clustering requires GTPase activity (PubMed:27920125). It may involve a major rearrangement of the coiled coil domains (PubMed:27920125, PubMed:28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12475957, PubMed:12759376). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed:12759376). Has low GTPase activity (PubMed:27920125, PubMed:28114303). {ECO:0000269|PubMed:12475957, ECO:0000269|PubMed:12759376, ECO:0000269|PubMed:27920125, ECO:0000269|PubMed:28114303}.

Research_area:

Applications:ELISA

Target_protein:MFN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.11ng/ml

Detection range:0.25-16ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Mitofusin-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8IWA4

MASS(Da):84160

GeneID:55669

Synonyms:MFN1

Gene names:MFN1

Standard solution:32ng/ml