Human Microtubule-associated Proteins 1A, 1B Light Chain 3A, MAPILC3A ELISA Kit

SKU: E6855Hu

Size:96 Tests-1 Kit

Background:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed: 20713600, PubMed: 24290141). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed: 20713600). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed: 31006538, PubMed: 31006537).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:MAP1LC3A

Reactivity:Human

Assay type:Sandwich

Sensitivity:11.63ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Microtubule-Associated Proteins 1A, 1B Light Chain 3A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H492

MASS(Da):14,272

GeneID:84557

Synonyms:Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;MAP1 light chain 3-like protein 1;MAP1A/MAP1B LC3 A;MAP1A/MAP1B light chain 3 A;MAP1LC3A;Microtubule-associated protein 1 light chain 3 alpha;Microtubule-associated proteins 1A/1B light chain 3A

Gene names:MAP1LC3A

Standard solution:6400ng/L