Human Methylated-DNA--protein-cysteine methyltransferase,MGMT ELISA KIT

SKU: E0707Hu

Size:96 Tests-1 Kit

Background:Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Research_area:

Applications:ELISA

Target_protein:MGMT

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.09ng/mL

Detection range:0.19-12ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:O6-methylguanine-DNA methyltransferase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P16455

MASS(Da):21646

GeneID:4255

Synonyms:MGMT

Gene names:MGMT

Standard solution:24ng/mL