Human MEP1A ELISA Kit PicoKine®

SKU: EK1552

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: MEP1A

Specificity:

Background: Meprin A subunit alpha also known as endopeptidase-2 or PABA peptide hydrolase is the alpha subunit of the meprin A enzyme that in humans is encoded by the MEP1A gene. Meprin A subunit alpha, encoded by the **MEP1A** gene, is a component of the meprin A metalloproteinase complex, which is involved in extracellular matrix remodeling and proteolysis. Meprin A is a zinc-dependent endopeptidase found predominantly in the kidneys, intestines, and other tissues. It plays a crucial role in various physiological processes, including inflammation, tissue repair, and the processing of bioactive peptides. The alpha subunit, specifically, is a part of the hetero-oligomeric enzyme complex, which combines with the beta subunit to form an active enzyme. Abnormalities in meprin A function have been associated with several pathological conditions, including kidney diseases and cancer.

Immunogen: Expression system for standard: NS0; Immunogen sequence: V22-Q601

Clonality:

Contents:

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Reconstitution:

Reference:

Uniprot ID: Q16819

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 4224

Protein Name: Meprin A subunit alpha

Gene Full Name: meprin A subunit alpha

Synonyms: Endopeptidase 2; MEP1A; Meprin A subunit alpha; PABA peptide hydrolase; PPH alpha; PPHA